Morphometric Changes of the Socket after Site Preservation Using Nanobone and Collagen Membrane or Stypro Versus Extraction Alone

Statement of Problem: The long-term success of a dental implant relies on implant osseointegration into native and viable bone, implant placement in an ideal position, and optimal hard and soft tissue contour. This requires the presence of sufficient alveolar bone volume, good alveolar ridge (Practically with no sign of atrophy) and good surgical technique.  Objectives: The aim of this randomized controlled clinical study was to evaluate morphometric changes after different alveolar ridge preservation procedures.Materials and Methods: In this study, 33 patients who had single-rooted premolar, which needed to be extracted, were recruited. Patients were randomly divided into 3 groups and after tooth extraction the following treatments were administered: in group A: NanoBone and a collagen membrane; in group B: NanoBone and Stypro; and in group C: natural healing. The following clinical parameters were evaluated at baseline and 6 months after the extraction: buccolingual width, midbuccal height (with the use of a custom made stent) and width of keratinized gingiva. For data analysis, Paired t-test,one-way ANOVA and Tukey’s tests were used.Results: The average reduction in the buccolingual width, midbuccal height and keratinized gingiva was as follows: group A: 1.18±0.6, 0.64±0.92 and 3.45±1.75 mm; group B: 2.18±0.75, 0.73±0.78 and 4.73±0.9 mm; and group C: 1±0.89, 2.36±1.21 and 5±0.63 mm, respectively. Moreover, a significantly reduced resorption was found in both the buccolingual width and the width of keratinized gingiva in group A as compared to groups B and C (p<0.05).Conclusions: This study showed that the use of collagen membrane+Nano bone (group A) can significantly reduce the horizontal resorption of the alveolar ridge and keratinized tissue more effectively than stypro+Nano bone (group B ) and blood clot alone and natural healing (group C).